发明授权
US07244738B2 Arylamine-substituted quinazolinone compounds useful as alpha 1A/B adrenergic receptor antagonists
失效
可用作α1A / B肾上腺素能受体拮抗剂的芳胺取代的喹唑啉酮化合物
- 专利标题: Arylamine-substituted quinazolinone compounds useful as alpha 1A/B adrenergic receptor antagonists
- 专利标题(中): 可用作α1A / B肾上腺素能受体拮抗剂的芳胺取代的喹唑啉酮化合物
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申请号: US10884768申请日: 2004-07-02
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公开(公告)号: US07244738B2公开(公告)日: 2007-07-17
- 发明人: Terrence Joseph Connolly , Paul Francis Keitz , Eun Kyung Lee , Jim Li , Francisco Javier Lopez-Tapia , Patrick Finbar McGarry , Chris Richard Melville , Dov Nitzan , Counde O'Yang , Fernando Padilla , Klaus Kurt Weinhardt
- 申请人: Terrence Joseph Connolly , Paul Francis Keitz , Eun Kyung Lee , Jim Li , Francisco Javier Lopez-Tapia , Patrick Finbar McGarry , Chris Richard Melville , Dov Nitzan , Counde O'Yang , Fernando Padilla , Klaus Kurt Weinhardt
- 申请人地址: US CA Palo Alto
- 专利权人: Roche Palo Alto LLC
- 当前专利权人: Roche Palo Alto LLC
- 当前专利权人地址: US CA Palo Alto
- 代理商 Robert C. Hall
- 主分类号: A61K31/517
- IPC分类号: A61K31/517 ; A01N43/54 ; C07D239/72 ; A61K31/549 ; C07D417/02 ; C07D285/26
摘要:
Compounds represented by Formula I: which are useful as are alpha-1A/B adrenoceptor antagonists, to methods of treating conditions associated with the activity of alpha-1A/B adrenoceptors, and to methods of making said compounds, wherein Ar, Z, R, R′, R5 and R10 are as defined herein.
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