发明授权
- 专利标题: Therapeutic compositions
- 专利标题(中): 治疗组合物
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申请号: US10841950申请日: 2004-05-07
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公开(公告)号: US07250401B2公开(公告)日: 2007-07-31
- 发明人: John V. Schloss
- 申请人: John V. Schloss
- 申请人地址: US KS Lawrence
- 专利权人: Advanced Therapeutics and Diagnostics, LC
- 当前专利权人: Advanced Therapeutics and Diagnostics, LC
- 当前专利权人地址: US KS Lawrence
- 代理机构: Schwegman, Lundberg, Woessner & Kluth
- 主分类号: A61K38/00
- IPC分类号: A61K38/00
摘要:
A method is provided for the preparation of compounds of the formula (R1)(R2)NC(═X)S(O)nR3 or (R1)(R2)NC(═X)OS(O)nR3, wherein R1, R2 and R3, X and n have any of the meanings defined in the specification. A method is also provided for the detection and quantitation of compounds of the formula (R1)(R2)NC(═X)OS(O)nR3. A method to link a therapeutic agent to a compound that is conjugated to glutathione is also provided for the purpose of improving the therapeutic properties of the therapeutic agent. Novel compounds, intermediates, pharmaceutical compositions and methods of use are also provided.
公开/授权文献
- US20050130904A1 Therapeutic compositions 公开/授权日:2005-06-16
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