发明授权
US07253190B2 Heteroaryl substituted tetrazole modulators of metabotrophic glutamate receptor-5
有权
代谢型谷氨酸受体-5的杂芳基取代四唑调节剂
- 专利标题： Heteroaryl substituted tetrazole modulators of metabotrophic glutamate receptor-5
- 专利标题（中）： 代谢型谷氨酸受体-5的杂芳基取代四唑调节剂
-
申请号： US10491613申请日： 2002-10-01
-
公开(公告)号： US07253190B2公开(公告)日： 2007-08-07
- 发明人: Nicholas D. P. Cosford , Chixu Chen , Thomas S. Reger , Jeffrey R. Roppe , Nicholas D. Smith
- 申请人： Nicholas D. P. Cosford , Chixu Chen , Thomas S. Reger , Jeffrey R. Roppe , Nicholas D. Smith
- 申请人地址： US NJ Rahway
- 专利权人： Merck & Co., Inc.
- 当前专利权人： Merck & Co., Inc.
- 当前专利权人地址： US NJ Rahway
- 代理商 David Rubin; William Krovatin
- 国际申请： PCT/US02/31294 WO 20021001
- 国际公布： WO03/029210 WO 20030410
- 主分类号： A61K31/4439
- IPC分类号： A61K31/4439 ; C07D401/04
摘要：
Tetrazole compounds substituted directly, or by a bridge, with a heteroaryl moiety containing N adjacent to the point of connection of the heteroaryl, are mGluR5 modulators useful in the treatment of psychiatric and mood disorders such as, for example, schizophrenia, anxiety, depression, and panic, as well as in the treatment of pain and other diseases.
公开/授权文献
信息查询
IPC分类:
