发明授权
US07256189B2 3-(4-amidopyrrol-2-ylmethylidene)-2-indolinone der derivatives as protein kinase inhibitors
失效
3-（4-氨基吡咯-2-基亚甲基）-2-二氢吲哚衍生物作为蛋白激酶抑制剂
- 专利标题： 3-(4-amidopyrrol-2-ylmethylidene)-2-indolinone der derivatives as protein kinase inhibitors
- 专利标题（中）： 3-（4-氨基吡咯-2-基亚甲基）-2-二氢吲哚衍生物作为蛋白激酶抑制剂
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申请号： US11511981申请日： 2006-08-28
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公开(公告)号： US07256189B2公开(公告)日： 2007-08-14
- 发明人: Huiping Guan , Congxin Liang , Li Sun , Peng Cho Tang , Chung Chen Wei , Tomas Vojkovsky , Qingwu (Alan) Jin , Paul M. Herrinton , Michael A. Mauragis
- 申请人： Huiping Guan , Congxin Liang , Li Sun , Peng Cho Tang , Chung Chen Wei , Tomas Vojkovsky , Qingwu (Alan) Jin , Paul M. Herrinton , Michael A. Mauragis
- 申请人地址： US NY New York US MI Kalamazoo
- 专利权人： Sugen, Inc.,Pharmacia & Upjohn Company
- 当前专利权人： Sugen, Inc.,Pharmacia & Upjohn Company
- 当前专利权人地址： US NY New York US MI Kalamazoo
- 代理商 Ye Hua; Stephen D. Prodnuk; Bryan C. Zielinski
- 主分类号： A61K31/5377
- IPC分类号： A61K31/5377 ; C07D413/14
摘要：
The present invention relates to pyrrole substituted 2-indolinone compounds and their pharmaceutically acceptable salts which modulate the activity of protein kinases and therefore are expected to be useful in the prevention and treatment of protein kinase related cellular disorders such as cancer.