发明授权
US07262272B2 Polypeptide compositions formed using a coiled-coil template and methods of use
有权
使用螺旋线圈模板和使用方法形成的多肽组合物
- 专利标题: Polypeptide compositions formed using a coiled-coil template and methods of use
- 专利标题(中): 使用螺旋线圈模板和使用方法形成的多肽组合物
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申请号: US11059582申请日: 2005-02-15
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公开(公告)号: US07262272B2公开(公告)日: 2007-08-28
- 发明人: Leslie H. Kondejewski , Randall T. Irvin , Robert S. Hodges
- 申请人: Leslie H. Kondejewski , Randall T. Irvin , Robert S. Hodges
- 申请人地址: unknown Edmonton, Alberta
- 专利权人: The Governors of the University of Alberta
- 当前专利权人: The Governors of the University of Alberta
- 当前专利权人地址: unknown Edmonton, Alberta
- 代理机构: Fish & Richardson P.C.
- 主分类号: A61K38/00
- IPC分类号: A61K38/00 ; A61K39/00 ; C12P21/08
摘要:
The invention relates to the use of constrained coiled-coil polypeptides to mimic α-helical structural elements of native proteins. These constrained peptidyl mimetics are used to generate and/or identify ligands which selectively bind the α-helical segment contained in the native protein.
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