Invention Grant
- Patent Title: Inhibitors of kinases
- Patent Title (中): 激酶抑制剂
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Application No.: US11035248Application Date: 2005-01-13
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Publication No.: US07265113B2Publication Date: 2007-09-04
- Inventor: Rajeev S. Bhide , Zhen-Wei Cai , Ligang Qian , Stephanie Barbosa , Louis Lombardo , Jeffrey Robl
- Applicant: Rajeev S. Bhide , Zhen-Wei Cai , Ligang Qian , Stephanie Barbosa , Louis Lombardo , Jeffrey Robl
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agent Elliott Korsen
- Main IPC: C07D487/04
- IPC: C07D487/04 ; A61K31/53 ; A61P35/00
Abstract:
The present invention provides compounds of formula I, and pharmaceutically acceptable salts thereof. The formula I compounds inhibit the tyrosine kinase activity of growth factor receptors such as VEGFR-2 and FGFR-1, thereby making them useful as anti-cancer agents. The formula I compounds are also useful for the treatment of other diseases associated with signal transduction pathways operating through growth factor receptors.
Public/Granted literature
- US20050124621A1 Novel inhibitors of kinases Public/Granted day:2005-06-09
Information query
