发明授权
- 专利标题: Anti-CD45RB antibodies
- 专利标题(中): 抗CD45RB抗体
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申请号: US10309764申请日: 2002-12-02
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公开(公告)号: US07265212B2公开(公告)日: 2007-09-04
- 发明人: John S. Babcook , Ian Foltz , Chadwick T. King , Varghese Palathumpat , Xiao-Dong Yang
- 申请人: John S. Babcook , Ian Foltz , Chadwick T. King , Varghese Palathumpat , Xiao-Dong Yang
- 申请人地址: US CA South San Francisco
- 专利权人: Amgen Fremont Inc.
- 当前专利权人: Amgen Fremont Inc.
- 当前专利权人地址: US CA South San Francisco
- 代理机构: Knobbe, Martens, Olson & Bear LLP
- 主分类号: C07K16/28
- IPC分类号: C07K16/28 ; G01N33/53
摘要:
Antibodies which specifically recognize the human CD45 isoform RB are presented. These antibodies may be used to block undesirable immune reactions in patients with transplant rejection and autoimmune diseases such as rheumatoid arthritis, multiple sclerosis and autoimmune diabetes. Preferred antibodies are fully human, monoclonal antibodies.
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