发明授权
- 专利标题： Ring fused pyrazole derivatives as CRF antagonists
- 专利标题（中）： 环稠合吡唑衍生物作为CRF拮抗剂
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申请号： US11348036申请日： 2006-02-06
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公开(公告)号： US07268146B2公开(公告)日： 2007-09-11
- 发明人: David Garrett Loughhead , Counde O'Yang
- 申请人： David Garrett Loughhead , Counde O'Yang
- 申请人地址： US CA Palo Alto
- 专利权人： Palo Alto LLC
- 当前专利权人： Palo Alto LLC
- 当前专利权人地址： US CA Palo Alto
- 代理商 Brian L. Buckwalter
- 主分类号： A01N43/42
- IPC分类号： A01N43/42 ; A61K31/44 ; C07D471/02 ; C07D491/02 ; C07D498/02
摘要：
This invention relates to compounds which are generally CRF-1 receptor antagonists and which are represented by Formula I or Formula II: wherein Ar is optionally substituted aryl or heteroaryl, R1-R4 are as defined in the specification; or individual isomers, racemic or non-racemic mixtures of isomers, or pharmaceutically acceptable salts thereof. The invention further relates to processes for preparing such compounds, to pharmaceutical compositions containing such compounds, and to methods for their use as therapeutic agents.
公开/授权文献
- US20060135555A1 Ring fused pyrazole derivatives as CRF antagonists 公开/授权日：2006-06-22