发明授权
US07273852B2 Synthetic C-glycolipid and its use for treating cancer, infectious diseases and autoimmune diseases
有权
合成β-糖脂及其用于治疗癌症,感染性疾病和自身免疫性疾病的用途
- 专利标题: Synthetic C-glycolipid and its use for treating cancer, infectious diseases and autoimmune diseases
- 专利标题(中): 合成β-糖脂及其用于治疗癌症,感染性疾病和自身免疫性疾病的用途
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申请号: US10462211申请日: 2003-06-13
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公开(公告)号: US07273852B2公开(公告)日: 2007-09-25
- 发明人: Moriya Tsuji , Guangwu Chen , Richard Franck , Guangli Yang
- 申请人: Moriya Tsuji , Guangwu Chen , Richard Franck , Guangli Yang
- 申请人地址: US NY New York
- 专利权人: The Research Foundation of the City University of New York
- 当前专利权人: The Research Foundation of the City University of New York
- 当前专利权人地址: US NY New York
- 代理机构: Darby & Darby
- 主分类号: A61K31/70
- IPC分类号: A61K31/70
摘要:
The invention is directed to compounds of formula (I) wherein X is O or NH; R′ is a hydrocarbon chain; R3 and R4 are hydrogen, OH or a monosaccharide; R5 is hydrogen or a monosaccharide; Q′ is optionally present and may be a C1-10 hydrocarbon; X′ is optionally present and may be O, S or NR8; and Q3 may be a hydrocarbon or hydrogen. The invention is also directed to the use of the compounds for treating cancer, infectious diseases and autoimmune diseases. The invention is also directed to syntheses of the compounds of formula (I).
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