发明授权
US07287646B2 Esters of 5-aminolevulinic acid and their use as photosensitizing compounds in photochemotherapy
有权
5-氨基乙酰丙酸的酯及其在光化学疗法中作为光敏化合物的用途
- 专利标题： Esters of 5-aminolevulinic acid and their use as photosensitizing compounds in photochemotherapy
- 专利标题（中）： 5-氨基乙酰丙酸的酯及其在光化学疗法中作为光敏化合物的用途
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申请号： US10966408申请日： 2004-10-14
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公开(公告)号： US07287646B2公开(公告)日： 2007-10-30
- 发明人: Karl E Gierskcky , Johan Moan , Qian Peng , Harald Steen , Trond Warloe , Alf Bjorseth , Jo Klaveness , Nils Nilsen , Jon Erik Braenden , Aslak Godal
- 申请人： Karl E Gierskcky , Johan Moan , Qian Peng , Harald Steen , Trond Warloe , Alf Bjorseth , Jo Klaveness , Nils Nilsen , Jon Erik Braenden , Aslak Godal
- 申请人地址： NO Oslo
- 专利权人： Photocure ASA
- 当前专利权人： Photocure ASA
- 当前专利权人地址： NO Oslo
- 代理机构： Kenyon & Kenyon LLP
- 优先权： GB9504948.2 19950310; GB9525822.4 19951218
- 主分类号： B65D69/00
- IPC分类号： B65D69/00 ; A61K31/22 ; C07C69/66
摘要：
The present invention relates to compounds being esters of 5-aminolevulinic acids or pharmaceutically acceptable salts thereof, including compounds of formula (I) R22N—CH2COCH2—CH2CO—OR1 (wherein R1 may represent alkyl optionally substituted by hydroxy, alkoxy, acyloxy, alkoxycarbonyloxy, amino, aryl, oxo or fluoro groups and optionally interrupted by oxygen, nitrogen, sulphur or phosphorus atoms; and R2 represents a hydrogen atom or a group R1, and both R2 groups may be the identical or different), and their use in diagnosis and photochemotherapy of disorders or abnormalities of external or internal surfaces of the body, and products and kits for performing the invention.
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