发明授权
- 专利标题: Pyrimidine compounds useful as N-type calcium channel antagonists
- 专利标题(中): 可用作N型钙通道拮抗剂的嘧啶化合物
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申请号: US10387543申请日: 2003-03-14
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公开(公告)号: US07288544B2公开(公告)日: 2007-10-30
- 发明人: Seiji Ohno , Kayo Otani , Seiji Niwa , Satoshi Iwayama , Akira Takahara , Hajime Koganei , Yukitsugu Ono , Shinichi Fujita , Tomoko Takeda , Masako Hagihara , Akiko Okajima
- 申请人: Seiji Ohno , Kayo Otani , Seiji Niwa , Satoshi Iwayama , Akira Takahara , Hajime Koganei , Yukitsugu Ono , Shinichi Fujita , Tomoko Takeda , Masako Hagihara , Akiko Okajima
- 申请人地址: JP Tokyo
- 专利权人: Ajinomoto Co., Inc.
- 当前专利权人: Ajinomoto Co., Inc.
- 当前专利权人地址: JP Tokyo
- 代理机构: Oblon, Spivak, McClelland, Maier & Neustadt, P.C.
- 优先权: JP2000-280438 20000914; JP2001-126832 20010425
- 主分类号: C07D239/338
- IPC分类号: C07D239/338 ; C07D403/04 ; A61K31/505
摘要:
Achiral pyrimidine derivatives and pyridine derivatives of the following formulae or analogs thereof have selective N-type calcium channel antagonistic activity and showed analgesic action when they were taken orally. They are useful as therapeutic agents for pains and various diseases associated with the N-type calcium channels
公开/授权文献
- US20040009991A1 Pyrimidine derivatives and new pyridine derivatives 公开/授权日:2004-01-15