发明授权
US07304082B2 1,2,4-triazole derivatives, compositions, process of making and methods of use
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1,2,4-三唑衍生物,组合物,制备方法和使用方法
- 专利标题: 1,2,4-triazole derivatives, compositions, process of making and methods of use
- 专利标题(中): 1,2,4-三唑衍生物,组合物,制备方法和使用方法
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申请号: US11186519申请日: 2005-07-21
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公开(公告)号: US07304082B2公开(公告)日: 2007-12-04
- 发明人: Joseph P. Marino, Jr. , Scott K. Thompson , Daniel Frank Veber
- 申请人: Joseph P. Marino, Jr. , Scott K. Thompson , Daniel Frank Veber
- 申请人地址: US PA Philadelphia
- 专利权人: SmithKline Beecham Corporation
- 当前专利权人: SmithKline Beecham Corporation
- 当前专利权人地址: US PA Philadelphia
- 代理商 Kathryn L. Sieburth; Mary E. McCarthy; Charles M. Kinzig
- 主分类号: A61K31/4196
- IPC分类号: A61K31/4196 ; C07D249/14
摘要:
Compounds of this invention are non-peptide, reversible inhibitors of type 2 methionine aminopeptidase, useful in treating conditions mediated by angiogenesis, such as cancer, haemangioma, proliferative retinopathy, rheumatoid arthritis, atherosclerotic neovascularization, psoriasis, ocular neovascularization and obesity.
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