发明授权
US07306922B2 Human and rat PGC-3, PPAR-gamma coactivations and splice variants thereof
失效
人和大鼠PGC-3，PPAR-γ共活化及其剪接变体
- 专利标题： Human and rat PGC-3, PPAR-gamma coactivations and splice variants thereof
- 专利标题（中）： 人和大鼠PGC-3，PPAR-γ共活化及其剪接变体
-
申请号： US10380492申请日： 2001-09-12
-
公开(公告)号： US07306922B2公开(公告)日： 2007-12-11
- 发明人: Kevin Anthony Hart , Carl Thomas Montague , Antonio Vidal-Puig
- 申请人： Kevin Anthony Hart , Carl Thomas Montague , Antonio Vidal-Puig
- 申请人地址： SE Sodertalje
- 专利权人： AstraZeneca AB
- 当前专利权人： AstraZeneca AB
- 当前专利权人地址： SE Sodertalje
- 代理机构： Ropes & Gray LLP
- 优先权： GB0022670.4 20000915
- 国际申请： PCT/GB01/04074 WO 20010912
- 国际公布： WO02/22818 WO 20020321
- 主分类号： G01N33/53
- IPC分类号： G01N33/53 ; C07H21/04
摘要：
A novel gene PGC-3, and its role in regulating the transcriptional activity of PPARγ in adipose tissue. PGC-3 is highly expressed in human white adipose tissue and has utility in the development of new therapeutic agents for use in the treatment of obesity and other related disorders such as non-insulin dependent diabetes mellitus, insulin resistance syndrome, dyslipidemia, and atherosclerosis.
公开/授权文献
信息查询
IPC分类:
