发明授权
US07314937B2 Non-imidazole aryl alkylamines compounds as histamine H3 receptor antagonists, preparation and therapeutic uses
失效
非咪唑芳基烷基胺化合物作为组胺H3受体拮抗剂,制备和治疗用途
- 专利标题: Non-imidazole aryl alkylamines compounds as histamine H3 receptor antagonists, preparation and therapeutic uses
- 专利标题(中): 非咪唑芳基烷基胺化合物作为组胺H3受体拮抗剂,制备和治疗用途
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申请号: US10472675申请日: 2002-03-21
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公开(公告)号: US07314937B2公开(公告)日: 2008-01-01
- 发明人: Lisa Selsam Beavers , Robert Alan Gadski , Philip Arthur Hipskind , Craig William Lindsley , Karen Lynn Lobb , James Arthur Nixon , Richard Todd Pickard , John Mehnert Schaus , Takako Takakuwa , Brian Morgan Watson
- 申请人: Lisa Selsam Beavers , Robert Alan Gadski , Philip Arthur Hipskind , Craig William Lindsley , Karen Lynn Lobb , James Arthur Nixon , Richard Todd Pickard , John Mehnert Schaus , Takako Takakuwa , Brian Morgan Watson
- 申请人地址: US IN Indianapolis
- 专利权人: Eli Lilly and Company
- 当前专利权人: Eli Lilly and Company
- 当前专利权人地址: US IN Indianapolis
- 代理商 Dan L. Wood
- 国际申请: PCT/US02/06644 WO 20020321
- 国际公布: WO02/076925 WO 20021003
- 主分类号: C07D217/22
- IPC分类号: C07D217/22 ; A61K31/47
摘要:
The present invention discloses novel substituted aryl alkylamine compounds of Formula (I) or pharmaceutically acceptable salts thereof which have selective histamine-H3 receptor antagonist activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such cyclic amines as well as methods of using them to treat obesity and other histamine H3 receptor-related diseases
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