发明授权
- 专利标题： Sertraline hydrochloride form II and methods for the preparation thereof
- 专利标题（中）： 舍曲林盐酸盐Ⅱ型及其制备方法
-
申请号： US11580589申请日： 2006-10-12
-
公开(公告)号： US07319171B2公开(公告)日： 2008-01-15
- 发明人: Eduard Schwartz , Tamar Nidam , Anita Liberman , Marioara Mendelovici , Judith Aronhime
- 申请人： Eduard Schwartz , Tamar Nidam , Anita Liberman , Marioara Mendelovici , Judith Aronhime
- 申请人地址： IL Petah Tiqva
- 专利权人： Teva Pharmaceutical Industries Ltd.
- 当前专利权人： Teva Pharmaceutical Industries Ltd.
- 当前专利权人地址： IL Petah Tiqva
- 代理机构： Kenyon & Kenyon LLP
- 主分类号： C07C211/42
- IPC分类号： C07C211/42 ; C07C211/19
摘要：
The present invention is directed to Form II of sertraline hydrochloride and novel methods for its preparation. According to the present invention, sertraline hydrochloride Form II may be produced directly form sertraline base or sertraline mandelate. It may also be produced from sertraline hydrochloride solvate and hydrate forms, and crystallized from new solvent systems. Pharmaceutical compositions containing sertraline hydrochloride Form II and methods of treatment using such pharmaceutical compositions are also disclosed.
公开/授权文献
信息查询
