发明授权
- 专利标题: Nucleotide derivative and DNA microarray
- 专利标题(中): 核苷酸衍生物和DNA微阵列
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申请号: US10746157申请日: 2003-12-24
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公开(公告)号: US07323555B2公开(公告)日: 2008-01-29
- 发明人: Isao Saito , Akimitsu Okamoto , Yasuko Yoshida
- 申请人: Isao Saito , Akimitsu Okamoto , Yasuko Yoshida
- 申请人地址: JP Kyoto JP Nagoya
- 专利权人: Isao Saito,NGK Insulators, Ltd.
- 当前专利权人: Isao Saito,NGK Insulators, Ltd.
- 当前专利权人地址: JP Kyoto JP Nagoya
- 代理机构: Oliff & Berridge PLC
- 主分类号: C07H21/02
- IPC分类号: C07H21/02 ; C07H21/04 ; G01N33/53 ; C12Q1/68
摘要:
A novel nucleotide derivative, in case of existing as a member of a single-stranded sequence, undergoing a change in the fluorescent signal intensity depending on the corresponding base type in the partner strand with which the single-stranded sequence is hybridized, and which is (1) a thymine/uracil derivative emitting light most intensely when a confronting base in the partner strand with which the single-stranded nucleotide sequence is hybridized is adenine; (2) a cytosine derivative emitting light most intensely when the confronting base is guanine; (3) an adenine derivative emitting light most intensely when the confronting base is cytosine; and, (4) a guanine derivative emitting light most intensely when the confronting base is cytosine or thymine/uracil.
公开/授权文献
- US20040186281A1 Nucleotide derivative and DNA microarray 公开/授权日:2004-09-23