发明授权
- 专利标题： Methods of crystal precipitation
- 专利标题（中）： 晶体析出方法
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申请号： US10527317申请日： 2003-09-17
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公开(公告)号： US07329318B2公开(公告)日： 2008-02-12
- 发明人: Shigeya Yamazaki , Taichi Yoshikawa
- 申请人： Shigeya Yamazaki , Taichi Yoshikawa
- 申请人地址： JP Tokyo
- 专利权人： Sumitomo Chemical Company, Limited
- 当前专利权人： Sumitomo Chemical Company, Limited
- 当前专利权人地址： JP Tokyo
- 代理机构： Birch, Stewart, Kolasch & Birch, LLP.
- 优先权： JP2002-273901 20020919
- 国际申请： PCT/JP03/11805 WO 20030917
- 国际公布： WO2004/026860 WO 20040401
- 主分类号： C30B7/04
- IPC分类号： C30B7/04
摘要：
Crystals of paroxetine hydrochloride ½-hydrate are allowed to separate out by adding water to a solution or suspension comprising paroxetine hydrochloride and a polar organic solvent which contains no water or at most 60% by weight of water to adjust the water content to at least 70% by weight when crystals of paroxetine hydrochloride ½-hydrate are allowed to separate out in a water-containing polar organic solvent. Crystals of paroxetine hydrochloride ½-hydrate being not colored in pink can be allowed to separate out in the presence of hydrogen chloride when crystals of paroxetine hydrochloride ½-hydrate are allowed to separate out in water or a water-containing polar organic solvent.
公开/授权文献
- US20060048696A1 Methods of crystal precipitation 公开/授权日：2006-03-09
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