发明授权
- 专利标题： Piperazinylcarbonylquinolines and -isoquinolines
- 专利标题（中）： 哌嗪基羰基喹啉和异喹啉
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申请号： US10466487申请日： 2001-12-24
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公开(公告)号： US07329749B2公开(公告)日： 2008-02-12
- 发明人: Henning Boettcher , Gerd Bartoszyk , Juergen Harting , Christoph van Amsterdam , Christoph Seyfried
- 申请人： Henning Boettcher , Gerd Bartoszyk , Juergen Harting , Christoph van Amsterdam , Christoph Seyfried
- 申请人地址： DE Darmstadt
- 专利权人： Merck Patent Gesellschaft
- 当前专利权人： Merck Patent Gesellschaft
- 当前专利权人地址： DE Darmstadt
- 代理机构： Millen, White, Zelano & Branigan, P.C.
- 优先权： DE10102053 20010117
- 国际申请： PCT/EP01/15311 WO 20011224
- 国际公布： WO02/057256 WO 20020725
- 主分类号： A61K31/496
- IPC分类号： A61K31/496 ; C07D403/06
摘要：
Compound of the formula (I) in which R1, R2 and alk are as defined in Claim 1, are potent 5-HT2A antagonist and are suitable for the treatment of psychoses, schizophrenia, depression, neurological disorders, memory disorders, Parkinson's disease, amyotrophic lateral sclerosis, Alzheimer's disease, Hutington's disease, eating disorders, such as bulimia, anorexia nervosa, premenstrual syndrome and/or for positively influencing obsessive-compulsive disorder (OCD).
公开/授权文献
- US20040077657A1 Piperazinylcarbonylquinolines and -isoquinolines 公开/授权日：2004-04-22
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