Invention Grant
US07332280B2 Classification of patients having diffuse large B-cell lymphoma based upon gene expression
有权
基于基因表达的弥漫性大B细胞淋巴瘤患者的分类
- Patent Title: Classification of patients having diffuse large B-cell lymphoma based upon gene expression
- Patent Title (中): 基于基因表达的弥漫性大B细胞淋巴瘤患者的分类
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Application No.: US10792374Application Date: 2004-03-03
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Publication No.: US07332280B2Publication Date: 2008-02-19
- Inventor: Ronald Levy , Mark A. Wechser , Izidore S. Lossos , Robert J. Tibshirani , Ash A. Alizadeh , David Botstein
- Applicant: Ronald Levy , Mark A. Wechser , Izidore S. Lossos , Robert J. Tibshirani , Ash A. Alizadeh , David Botstein
- Agency: Harness, Dickey & Pierce, P.L.C.
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; G01N33/574 ; G01N33/48
Abstract:
Methods and kits for classifying patients having diffuse large B-cell lymphoma (DLBCL) based upon expression of a plurality of genes are disclosed. Real-time quantitative RT-PCR can be used to measure expression values. Correlating expression values of the plurality of genes in a tumor sample from the patient to reference expression values obtained from DLBCL patients can stratify patients in the classification groups. The methods and kits can be used to predict overall patient survival.
Public/Granted literature
- US20050079513A1 Classification of patients having diffuse large B-cell lymphoma based upon gene expression Public/Granted day:2005-04-14
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