发明授权
US07335656B2 Medical devices employing triazine compounds and compositions thereof
失效
使用三嗪化合物的医疗装置及其组合物
- 专利标题： Medical devices employing triazine compounds and compositions thereof
- 专利标题（中）： 使用三嗪化合物的医疗装置及其组合物
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申请号： US11512863申请日： 2006-08-30
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公开(公告)号： US07335656B2公开(公告)日： 2008-02-26
- 发明人: Richard T. Timmer , Christopher W. Alexander , Sivaram Pillarisetti , Uday Saxena , Sesha Sridevi Alluri , Koteswar Rao Yeleswarapu , Manojit Pal , Jangalgar Tirupathy Reddy , Velagala Venkata Rama Murali Krishna Reddy , Potlapally Rajender Kumar , Gaddam Om Reddy
- 申请人： Richard T. Timmer , Christopher W. Alexander , Sivaram Pillarisetti , Uday Saxena , Sesha Sridevi Alluri , Koteswar Rao Yeleswarapu , Manojit Pal , Jangalgar Tirupathy Reddy , Velagala Venkata Rama Murali Krishna Reddy , Potlapally Rajender Kumar , Gaddam Om Reddy
- 申请人地址： US GA Norcross
- 专利权人： Reddy US Therapeutics, Inc.
- 当前专利权人： Reddy US Therapeutics, Inc.
- 当前专利权人地址： US GA Norcross
- 代理商 Robert Steve Thomas
- 主分类号： A61M31/00
- IPC分类号： A61M31/00 ; A61F2/86 ; C07D251/70 ; C07D251/52 ; C07D251/30 ; A61P35/00
摘要：
The present invention relates to methods, compounds, and compositions comprising compounds that treat pathophysiological conditions arising from inflammatory responses, and is directed to compounds that inhibit or block glycated protein produced induction of the signaling-associated inflammatory response in endothelial cells. The present invention also relates to compounds that inhibit smooth muscle proliferation, for example, by modulating HSPGs such as Perlecan. The present invention further relates to the use of compounds to treat vascular occlusive conditions characterized by smooth muscle proliferation such as restenosis and atherosclerosis. This invention also relates to medical devices, such as a stent, comprising a compound or composition of this invention disposed on or within the medical device.