发明授权
- 专利标题： Spirocyclic heterocyclic derivatives and methods of their use
- 专利标题（中）： 螺环杂环衍生物及其使用方法
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申请号： US10957554申请日： 2004-10-01
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公开(公告)号： US07338962B2公开(公告)日： 2008-03-04
- 发明人: Roland E. Dolle , Bertrand Le Bourdonnec
- 申请人： Roland E. Dolle , Bertrand Le Bourdonnec
- 申请人地址： US PA Exton
- 专利权人： Adolor Corporation
- 当前专利权人： Adolor Corporation
- 当前专利权人地址： US PA Exton
- 代理机构： Woodcock Washburn LLP
- 主分类号： A61K31/438
- IPC分类号： A61K31/438 ; C07D491/107
摘要：
Spirocyclic heterocyclic derivatives, pharmaceutical compositions containing these compounds, and methods for their pharmaceutical use are disclosed. In certain embodiments, the spirocyclic heterocyclic derivatives are ligands of the δ opioid receptor and may be useful, inter alia, for treating and/or preventing pain, anxiety, gastrointestinal disorders, and other δ opioid receptor-mediated conditions.
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