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US07339212B2 p channel filed effect transistor and sensor using the same 有权
p沟道场效应晶体管和使用其的传感器

p channel filed effect transistor and sensor using the same
摘要：
A p channel field effect transistor in which the sensitivity of an enzyme can be enhanced by immobilizing the enzyme directly on an FET channel surface (diamond surface), as well as a sensor including the same, is provided. A diamond surface (22) having mixed hydrogen terminals, oxygen terminals, and amino terminals is treated under the action of glutaraldehyde OHC(CH2)3CHO (30), so that the glutaraldehyde (30) is immobilized on the diamond surface (22) having mixed hydrogen terminals, oxygen terminals, and amino terminals. Subsequently, urease (29) is further applied thereto, so that the amino group (31) of the urease (29) is bonded to the glutaraldehyde (30). That is, the urease (29) can be immobilized on the diamond surface (22) having mixed hydrogen terminals, oxygen terminals, and amino terminals. When the urea concentration is increased from 10−6 M to 10−2 M, the threshold voltage shifts by about 0.1 V in the positive direction, and the sensitivity to urea concentration of 30 mV/decade is exhibited.
摘要（中）：

提供了一种p沟道场效应晶体管，其中通过将酶直接固定在FET沟道表面（金刚石表面）上以及包括其的传感器可以提高酶的灵敏度。 在戊二醛OHC（CH 2 CH 3）3 CHO（30）的作用下处理具有混合氢末端，氧末端和氨基末端的金刚石表面（22），因此 将戊二醛（30）固定在具有混合的氢末端，氧末端和氨基末端的金刚石表面（22）上。 随后，进一步施用脲酶（29），使脲酶（29）的氨基（31）与戊二醛（30）结合。 也就是说，脲酶（29）可以固定在具有混合氢末端，氧末端和氨基末端的金刚石表面（22）上。 当尿素浓度从10 -6 M增加到10 -2 M时，阈值电压在正方向偏移约0.1 V，对尿素浓度敏感 30 mV /十年。

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