A disk drive is adapted to a disk cartridge having a rotational member and a shutter interlocked with the rotational member. The drive includes a transporting portion for transporting the cartridge and a shutter driving mechanism, which includes a rack portion engaging with a gear portion of the rotational member, and first and second driving levers supported to fit into, and turn with, first and second notched portions of the rotational member, respectively. The transporting portion includes a first cam structure for driving the first and second driving levers of the shutter driving mechanism such that the levers swing as the transporting portion moves. As the transporting portion moves, the first and second notched portions and the gear portion of the disk cartridge held on the transporting portion get engaged with the shutter driving mechanism, which then rotates the rotational member to open or close the shutter.