发明授权
US07341990B2 Methods and uses of leukotriene B4 hydroxylases to treat diseases
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白三烯B4羟化酶治疗疾病的方法和用途
- 专利标题： Methods and uses of leukotriene B4 hydroxylases to treat diseases
- 专利标题（中）： 白三烯B4羟化酶治疗疾病的方法和用途
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申请号： US11414896申请日： 2006-05-01
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公开(公告)号： US07341990B2公开(公告)日： 2008-03-11
- 发明人: David R. Harder , James B. Antczak , Lane Brostrom
- 申请人： David R. Harder , James B. Antczak , Lane Brostrom
- 代理机构： Quarles & Brady LLP
- 主分类号： A61K37/00
- IPC分类号： A61K37/00 ; A61K31/70
摘要：
Methods and uses are described for treating or preventing diseases of humans or non-human animals by reducing the amount of active leukotriene B4 (LTB4) in those in need of such treatment using LTB4 hydroxylases. In certain embodiments, LTB4 hydroxylase is administered in combination with nicotinamide adenine dinucleotide phosphate and/or an NADPH-cytochrome P-450 reductase. The invention is particularly useful for treating or preventing respiratory diseases that are caused or exacerbated by inflammation.
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