发明授权
US07354933B2 Cyclic urea derivatives, preparation thereof and pharmaceutical use thereof as kinase inhibitors
失效
环状尿素衍生物，其制备方法及其作为激酶抑制剂的药物用途
- 专利标题： Cyclic urea derivatives, preparation thereof and pharmaceutical use thereof as kinase inhibitors
- 专利标题（中）： 环状尿素衍生物，其制备方法及其作为激酶抑制剂的药物用途
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申请号： US10770382申请日： 2004-02-02
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公开(公告)号： US07354933B2公开(公告)日： 2008-04-08
- 发明人: Marcel Patek , Anil Nair , Augustin Hittinger , Conception Nemecek , Daniel Bond , Greg Harlow , Herve Bouchard , Jacques Mauger , Jean-Luc Malleron , Mark Palermo , Fahad Al-Obeidi , Thomas Faitg , Hartmut Strobel , Sven Ruf , Kurt Ritter , Youssef El-Ahmad , Dominique Lesuisse , Didier Bénard
- 申请人： Marcel Patek , Anil Nair , Augustin Hittinger , Conception Nemecek , Daniel Bond , Greg Harlow , Herve Bouchard , Jacques Mauger , Jean-Luc Malleron , Mark Palermo , Fahad Al-Obeidi , Thomas Faitg , Hartmut Strobel , Sven Ruf , Kurt Ritter , Youssef El-Ahmad , Dominique Lesuisse , Didier Bénard
- 申请人地址： FR Antony
- 专利权人： Aventis Pharma SA
- 当前专利权人： Aventis Pharma SA
- 当前专利权人地址： FR Antony
- 代理商 Kelly L. Bender; Paul R. Darkes
- 优先权： FR0301098 20030131
- 主分类号： C07D401/06
- IPC分类号： C07D401/06 ; C07D403/06 ; A61K31/41
摘要：
The present invention relates to a cyclic urea compound of formula I: as defined herein. The invention is also directed to the process for its preparation, pharmaceutical composition comprising it and its pharmaceutical use, as an inhibitor on a protein kinase. Thus, it is useful for preventing or treating a physiological disorder capable of being modulated by inhibiting the activity of a protein kinase, such as a solid tumor.
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