Invention Grant
US07354941B2 Nicotinamide benzofused-heterocyclyl derivatives useful as selective inhibitors of PDE4 isozymes
失效
可用作PDE4同功酶选择性抑制剂的烟酰胺苯并吲哚杂环基衍生物
- Patent Title: Nicotinamide benzofused-heterocyclyl derivatives useful as selective inhibitors of PDE4 isozymes
- Patent Title (中): 可用作PDE4同功酶选择性抑制剂的烟酰胺苯并吲哚杂环基衍生物
-
Application No.: US10181416Application Date: 2001-01-30
-
Publication No.: US07354941B2Publication Date: 2008-04-08
- Inventor: Anthony Marfat , Robert James Chambers
- Applicant: Anthony Marfat , Robert James Chambers
- Applicant Address: US CT Groton
- Assignee: Pfizer Products Inc.
- Current Assignee: Pfizer Products Inc.
- Current Assignee Address: US CT Groton
- International Application: PCT/IB01/00124 WO 20010130
- International Announcement: WO01/57036 WO 20010809
- Main IPC: A61K31/465
- IPC: A61K31/465
Abstract:
Compounds useful as inhibitors of PDE4 in the treatment of diseases regulated by the activation and degranulation of eosinophils, especially asthma, chronic bronchitis, and chronic obstructive pulmonary disease, of Formula (1.0.0): wherein R5 and R6 are taken together to form a moiety of partial Formulas (1.1.1) through (1.1.5): or a pharmaceutically acceptable salt thereof.
Public/Granted literature
- US20030186989A1 Nicotinamide benzofused-heterocyclyl derivatives useful as selective inhibitors of pde4 isozymes Public/Granted day:2003-10-02
Information query
