The invention provides a printing control system for controlling a print-head. The printing control system includes a motor controller, a time-delaying generator coupled to the motor controller, and a timer coupled to the delay time generator. The motor controller is used for calculating the moving speed of the print-head reaching a printing position. The time-delaying generator is used for generating a delay time according to the moving speed. The timer is used for starting to count a printing time after the print-head reaches the printing position. When the printing time equals the delay time, the timer outputs a printing signal to control the print-head to jet out an ink drop.