发明授权
- 专利标题： Control of acute hypertension and cardiotoxicity in patients treated with vascular targeting agents
- 专利标题（中）： 控制血管靶向剂治疗的患者急性高血压和心脏毒性
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申请号： US10602325申请日： 2003-06-23
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公开(公告)号： US07358236B1公开(公告)日： 2008-04-15
- 发明人: David Chaplin , Scott Young
- 申请人： David Chaplin , Scott Young
- 申请人地址： US MA Waltham
- 专利权人： OXiGENE, Inc.
- 当前专利权人： OXiGENE, Inc.
- 当前专利权人地址： US MA Waltham
- 代理机构： Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C.
- 代理商 Ivor R. Elrifi; Naomi S. Biswas
- 主分类号： A61K31/66
- IPC分类号： A61K31/66 ; A61K31/075
摘要：
The present invention provides a method of using anti-hypertensive agents (“AHAs”) to attenuate the transient increase in blood pressure observed in patients where Vascular Targeting Agents (“VTAs”) are administered to treat diseases associated with malignant neovascularization. The invention also relates to pharmaceutical compositions comprising AHAs and VTAs, and to kits thereof.
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