发明授权
US07368098B2 Use of biomolecular targets in the treatment and visualization of tumors
有权
在肿瘤治疗和可视化中使用生物分子靶标
- 专利标题： Use of biomolecular targets in the treatment and visualization of tumors
- 专利标题（中）： 在肿瘤治疗和可视化中使用生物分子靶标
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申请号： US10328544申请日： 2002-12-23
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公开(公告)号： US07368098B2公开(公告)日： 2008-05-06
- 发明人: Sabine Mueller , Mirella Gonzalez-Zulueta , Erik Foehr , Daniel J. Chin
- 申请人： Sabine Mueller , Mirella Gonzalez-Zulueta , Erik Foehr , Daniel J. Chin
- 申请人地址： US NJ Princeton
- 专利权人： Medarex, Inc.
- 当前专利权人： Medarex, Inc.
- 当前专利权人地址： US NJ Princeton
- 代理机构： Lahive & Cockfield, LLP
- 代理商 Jane E. Remillard, Esq.
- 主分类号： G01N33/574
- IPC分类号： G01N33/574
摘要：
The present invention relates to the use of a protein that is differentially expressed in primary brain tumor tissues, as compared to normal brain tissues, as a biomolecular target for tumor treatment therapies. The protein is also expressed in tissues from adenocarcinoma, non-melanoma, and renal carcinoma cells. Immunotherapeutic and immunoimaging agents that specifically bind to an identified brain tumor target protein are provided. The present invention also provides compounds and pharmaceutically acceptable compositions for administration in the methods of the invention.
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