Invention Grant
US07371514B2 Serial derivatization of peptides for de novo sequencing using tandem mass spectrometry
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使用串联质谱法进行从头测序的肽的序列衍生化
- Patent Title: Serial derivatization of peptides for de novo sequencing using tandem mass spectrometry
- Patent Title (中): 使用串联质谱法进行从头测序的肽的序列衍生化
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Application No.: US10892870Application Date: 2004-07-16
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Publication No.: US07371514B2Publication Date: 2008-05-13
- Inventor: Barry E. Boyes , Gordon R. Nicol , Hongbin Liu
- Applicant: Barry E. Boyes , Gordon R. Nicol , Hongbin Liu
- Applicant Address: US CA Santa Clara
- Assignee: Agilent Technologies, Inc.
- Current Assignee: Agilent Technologies, Inc.
- Current Assignee Address: US CA Santa Clara
- Main IPC: C12Q1/00
- IPC: C12Q1/00
Abstract:
Serial derivatization by chemical reactions of analytes for mass spectrometry is disclosed. The derivatizations enhance the use of MS techniques for analyzing protein samples, particularly when the sequence of a polypeptide is determined by tandem MS/MS. Accurate mass analysis techniques are described for use in sequencing polypeptides, together with the use of sequencing data in protein analysis.
Public/Granted literature
- US20060014210A1 Serial derivatization of peptides for de novo sequencing using tandem mass spectrometry Public/Granted day:2006-01-19
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