A protection circuit of an LCD panel. The LCD panel includes a display cell coupled between a data electrode, a gate electrode and a common electrode. A switch includes a first terminal and a second terminal. The first terminal is coupled to the data electrode, the gate electrode or both. The switch is turned on when a voltage level of the first terminal or the second terminal exceeds a threshold voltage. An ESD protection circuit includes a capacitive load and a resistive load, coupled between the second terminal and the common electrode.