- 专利标题： Use of penetration enhancers and barrier disruption methods to enhance the immune response of antigen and adjuvant
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申请号： US10790715申请日： 2004-03-03
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公开(公告)号： US07378097B2公开(公告)日： 2008-05-27
- 发明人: Gregory M. Glenn , Carl R. Alving
- 申请人： Gregory M. Glenn , Carl R. Alving
- 申请人地址： US DC Washington
- 专利权人： The United States of America as represented by the Secretary of the Army
- 当前专利权人： The United States of America as represented by the Secretary of the Army
- 当前专利权人地址： US DC Washington
- 代理机构： Morgan, Lewis & Bockius LLP
- 主分类号： A61K45/00
- IPC分类号： A61K45/00
摘要：
A transcutaneous immunization system where the topical application of an adjuvant and an antigen or nucleic acid encoding for an antigen, to intact skin induces a systemic or mucosol antibody response. The immune response so elicited can be enhanced by physical or chemical skin penetration enhancement.
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