发明授权
US07381537B2 Use of inhibitors of glutaminyl cyclases for treatment and prevention of disease
有权
使用谷氨酰胺酰环化酶抑制剂治疗和预防疾病
- 专利标题： Use of inhibitors of glutaminyl cyclases for treatment and prevention of disease
- 专利标题（中）： 使用谷氨酰胺酰环化酶抑制剂治疗和预防疾病
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申请号： US10839017申请日： 2004-05-05
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公开(公告)号： US07381537B2公开(公告)日： 2008-06-03
- 发明人: Hans-Ulrich Demuth , Torsten Hoffmann , Andre J. Niestroj , Stephan Schilling , Ulrich Heiser
- 申请人： Hans-Ulrich Demuth , Torsten Hoffmann , Andre J. Niestroj , Stephan Schilling , Ulrich Heiser
- 申请人地址： DE Weinbergweg 22, Halle Saale
- 专利权人： Probiodrug AG
- 当前专利权人： Probiodrug AG
- 当前专利权人地址： DE Weinbergweg 22, Halle Saale
- 代理机构： Sonnenschein Nath & Rosenthal LLP
- 主分类号： C12Q1/34
- IPC分类号： C12Q1/34
摘要：
The present invention provides novel physiological substrates of mammalian glutaminyl cyclase (QC, EC 2.3.2.5), new effectors of QC, methods for screeing for such effectors, and the use of such effectors and pharmaceutical compositions comprising such effectors for the treatment of conditions that can be treated by modulation of QC-activity. Preferred compositions additionally comprise inhibitors of DP IV or DP IV-like enzymes for the treatment or alleviation of conditions that can be treated by modulation of QC- and DP IV-activity.
公开/授权文献
- US20050058635A1 Use of effectors of glutaminyl and glutamate cyclases 公开/授权日：2005-03-17
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