发明授权
- 专利标题: Human type antihuman IgE receptor antibody and fragment
- 专利标题(中): 人类抗人IgE受体抗体和片段
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申请号: US10484206申请日: 2002-07-18
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公开(公告)号: US07384633B2公开(公告)日: 2008-06-10
- 发明人: Kazuhisa Sugimura , Toshihiro Nakashima , Masaharu Torikai
- 申请人: Kazuhisa Sugimura , Toshihiro Nakashima , Masaharu Torikai
- 申请人地址: JP Kumamoto-ken
- 专利权人: Judicial Foundation the Chemo-Sero-Therapeutic Res.
- 当前专利权人: Judicial Foundation the Chemo-Sero-Therapeutic Res.
- 当前专利权人地址: JP Kumamoto-ken
- 代理机构: Browdy and Neimark
- 优先权: JP2001-219990 20010719
- 国际申请: PCT/JP02/07283 WO 20020718
- 国际公布: WO03/008584 WO 20030130
- 主分类号: A61K39/395
- IPC分类号: A61K39/395
摘要:
An antibody or an antibody fragment is provided that is efficacious for treating allergic diseases in which IgE is involved. A human antibody and a fragment thereof to a receptor (FcεRI) having high affinity to Fc portion of IgE was obtained using phage antibody display technique. The human anti-IgE receptor antibody and a fragment thereof of the invention has an activity to inhibit the binding between IgE and IgE receptor and hence is expected to be useful as a medicament for treating allergic diseases caused by the binding between IgE and IgE receptor.
公开/授权文献
- US20050170451A1 Human type antihuman ige receptor antibody and fragment 公开/授权日:2005-08-04
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