发明授权
- 专利标题: Metallopeptide compounds
- 专利标题(中): 金属肽化合物
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申请号: US11188552申请日: 2005-07-25
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公开(公告)号: US07385025B2公开(公告)日: 2008-06-10
- 发明人: Shubh D. Sharma , Yi-Qun Shi , Ramesh Rajpurohit , Hui-Zhi Cai , Margarita Bastos
- 申请人: Shubh D. Sharma , Yi-Qun Shi , Ramesh Rajpurohit , Hui-Zhi Cai , Margarita Bastos
- 申请人地址: US NJ Cranbury
- 专利权人: Palatin Technologies, Inc.
- 当前专利权人: Palatin Technologies, Inc.
- 当前专利权人地址: US NJ Cranbury
- 代理商 Stephen A. Slusher
- 主分类号: A61K38/04
- IPC分类号: A61K38/04 ; A61K51/08 ; C07K7/00
摘要:
Metallopeptides with a sequence of a biologically active alpha-melanocyte stimulating hormone (α-MSH), gamma-melanocyte stimulating hormone (γ-MSH), or bombesin sequence of length n residues, wherein a residue including a nitrogen atom and sulfur atom each available for complexation to a metal ion is inserted at any position from between the two and three position to the C-terminus side of the n position, or alternatively is substituted for the residue at any position from the three position to the n position, with a metal ion complexed thereto, with any proline (Pro) residue which is either of the two residues on the immediately adjacent N-terminus side of the inserted or substituent residue comprising a nitrogen atom and sulfur atom available for complexation to a metal ion is substituted with a homolog.
公开/授权文献
- US20050282739A1 Metallopeptide compounds 公开/授权日:2005-12-22