发明授权
- 专利标题： Soluble interleukin-1 receptor accessory molecule
- 专利标题（中）： 可溶性白细胞介素-1受体辅助分子
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申请号： US11066006申请日： 2005-02-25
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公开(公告)号： US07390880B2公开(公告)日： 2008-06-24
- 发明人: Daniel P. Bednarik , Henrik S. Olsen , Craig A. Rosen
- 申请人： Daniel P. Bednarik , Henrik S. Olsen , Craig A. Rosen
- 申请人地址： US MD Rockville
- 专利权人： Human Genome Sciences, Inc.
- 当前专利权人： Human Genome Sciences, Inc.
- 当前专利权人地址： US MD Rockville
- 主分类号： C07K14/00
- IPC分类号： C07K14/00 ; C07K14/52
摘要：
The present invention relates to a novel soluble IL-1 receptor accessory molecule (IL-1R AcM) protein which is a member of the Ig superfamily. In particular, isolated nucleic acid molecules are provided encoding the human IL-1R AcM protein. IL-1R AcM polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. Screening methods are futher provided for identifying agonist and antagonists of IL-1 signal transduction. The invention further relates to methods for treating physiologic and pathologic disease conditions with IL-1R AcM antagonists.
公开/授权文献
- US20050171337A1 Soluble interleukin-1 receptor accessory molecule 公开/授权日：2005-08-04
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