A wheel condition determination apparatus includes a primary sensor unit and a secondary sensor unit that are provided in the wheels of a vehicle. The primary sensor unit detects a predetermined parameter indicating the condition of the wheel and controls the operation mode of the secondary sensor unit in accordance with the detected predetermined parameter. The secondary sensor unit detects a predetermined parameter indicating the condition of the wheel that is different from the predetermined parameter detected by the primary sensor unit. The operation mode of the secondary sensor unit may be changed between an active mode and a sleep mode. In the sleep mode, detection of the wheel condition may be suspended or performed less frequently than as the active mode.