A tablet cassette in which a tablet is not discharged during a mounting or dismounting operation of the tablet cassette. The tablet cassette (1) incorporates a rotor (6) having pocket portions (7) for holding tablets (T). When the tablet cassette 1 is mounted on a mount base (2), rotation of the rotor (6) causes the tablets (T) held in the pocket portions (7) to be discharged though a discharge port (8). The tablet cassette (1) includes a press member (16) which is pressed when the tablet cassette (1) is mounted on the mount base (2) and a rotor reversing member (19) for reversing the rotor (6) by a predetermined quantity in conjunction with pressing of the press member (16).