发明授权
US07396834B2 4(Phenyl-piperazinyl-methyl) benzamide derivatives and their use for the treatment of pain or gastrointestinal disorders
失效
4（苯基 - 哌嗪基 - 甲基）苯甲酰胺衍生物及其用于治疗疼痛或胃肠道疾病的用途
- 专利标题： 4(Phenyl-piperazinyl-methyl) benzamide derivatives and their use for the treatment of pain or gastrointestinal disorders
- 专利标题（中）： 4（苯基 - 哌嗪基 - 甲基）苯甲酰胺衍生物及其用于治疗疼痛或胃肠道疾病的用途
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申请号： US10533744申请日： 2003-11-05
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公开(公告)号： US07396834B2公开(公告)日： 2008-07-08
- 发明人: William Brown , Andrew Griffin , Niklas Plobeck , Christopher Walpole
- 申请人： William Brown , Andrew Griffin , Niklas Plobeck , Christopher Walpole
- 申请人地址： SE Sodertalje
- 专利权人： AstraZeneca AB
- 当前专利权人： AstraZeneca AB
- 当前专利权人地址： SE Sodertalje
- 代理商 Jacqueline M. Cohen
- 优先权： SE0203300 20021107
- 国际申请： PCT/SE03/01703 WO 20031105
- 国际公布： WO2004/041800 WO 20040521
- 主分类号： A61K31/495
- IPC分类号： A61K31/495 ; A61K31/496 ; C07D295/155 ; C07D307/52
摘要：
Compounds of general formula: wherein R1 and R2 are as defined in the specification, as well as salts, enantiomers thereof and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.