发明授权
US07399779B2 3,6-disubstituted azabicyclo [3.1.0] hexane derivatives useful as muscarinic receptor antagonists
失效
用作毒蕈碱受体拮抗剂的3,6-二取代的氮杂双环[3.1.0]己烷衍生物
- 专利标题: 3,6-disubstituted azabicyclo [3.1.0] hexane derivatives useful as muscarinic receptor antagonists
- 专利标题(中): 用作毒蕈碱受体拮抗剂的3,6-二取代的氮杂双环[3.1.0]己烷衍生物
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申请号: US10520573申请日: 2002-07-08
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公开(公告)号: US07399779B2公开(公告)日: 2008-07-15
- 发明人: Anita Mehta , Arundutt V. Silamkoti , Jang Bahadur Gupta
- 申请人: Anita Mehta , Arundutt V. Silamkoti , Jang Bahadur Gupta
- 申请人地址: IN Gurgaon
- 专利权人: Ranbaxy Laboratories Limited
- 当前专利权人: Ranbaxy Laboratories Limited
- 当前专利权人地址: IN Gurgaon
- 代理商 Jayadeep R. Deshmukh, Esq.; George E. Heibel, Esq.
- 国际申请: PCT/IB02/02663 WO 20020708
- 国际公布: WO2004/004629 WO 20040115
- 主分类号: A61K31/403
- IPC分类号: A61K31/403 ; C07D209/52
摘要:
This invention generally relates to the derivatives of novel 3,6 disubstituted azabicyclo[3.1.0]hexanes. The compounds of this invention are muscarinic receptor antagonists which are useful, inter-alia for the treatment of various diseases of the respiratory, urinary and gastrointestinal systems mediated through muscarinic receptors. The invention also relates to pharmaceutical compositions containing the compounds of the present invention and the methods of treating the diseases mediated through muscarinic receptors.
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