发明授权
- 专利标题： Immunologically active polypeptides with altered toxicity useful for the preparation of an antipertussis vaccine
- 专利标题（中）： 具有改变的毒性的免疫活性多肽可用于制备抗百日咳疫苗
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申请号： US08261692申请日： 1994-06-17
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公开(公告)号： US07410646B1公开(公告)日： 2008-08-12
- 发明人: Mariagrazia Pizza , Antonella Bartoloni , Rino Rappuoli
- 申请人： Mariagrazia Pizza , Antonella Bartoloni , Rino Rappuoli
- 申请人地址： IT
- 专利权人： Novartis Vaccines and Diagnostics S.R.L.
- 当前专利权人： Novartis Vaccines and Diagnostics S.R.L.
- 当前专利权人地址： IT
- 代理机构： Woodcock Washburn LLP
- 优先权： IT22481/87 19871102
- 主分类号： A61K39/10
- IPC分类号： A61K39/10 ; C07K14/235
摘要：
Immunologically active polypeptides with no or reduced toxicity useful for the preparation of an antipertussis vaccine. Method for the preparation of said polypeptides which comprises, cultivating a microorganism transformed with a hybrid plasmid including the gene/s which codes for at least one of said polypeptides in a suitable medium and recovering the desired polypeptide from the cells or from the culture medium.
信息查询
