发明授权
- 专利标题: Pyrazole-amide compounds useful as kinase inhibitors
- 专利标题(中): 用作激酶抑制剂的吡唑酰胺化合物
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申请号: US10837778申请日: 2004-05-03
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公开(公告)号: US07414056B2公开(公告)日: 2008-08-19
- 发明人: Alaric J. Dyckman , Jagabandhu Das , Katerina Leftheris , Chunjian Liu , Robert V. Moquin , Stephen T. Wrobleski
- 申请人: Alaric J. Dyckman , Jagabandhu Das , Katerina Leftheris , Chunjian Liu , Robert V. Moquin , Stephen T. Wrobleski
- 申请人地址: US NJ Princeton
- 专利权人: Bristol-Myers Squibb Company
- 当前专利权人: Bristol-Myers Squibb Company
- 当前专利权人地址: US NJ Princeton
- 代理商 Laurelee A. Duncan; Rosemary A. Miano; Anastasia P. Winslow
- 主分类号: A61K31/501
- IPC分类号: A61K31/501 ; C07F9/02 ; C07D401/12 ; C07D271/06 ; C07D277/84
摘要:
The present invention provides pyrazole derived compounds of formula (I) useful for treating p38 kinase-associated conditions, where G, X, R1, R2, R3, R4, R5, R6 and m are as defined herein. The invention further pertains to pharmaceutical compositions containing at least one compound according to the invention useful for treating p38 kinase-associated conditions, and methods of inhibiting the activity of p38 kinase in a mammal.
公开/授权文献
- US20050004176A1 Pyrazole-amide compounds useful as kinase inhibitors 公开/授权日:2005-01-06