Invention Grant
- Patent Title: Phospholipase A2 and gene thereof
- Patent Title (中): 磷脂酶A2及其基因
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Application No.: US10501675Application Date: 2003-01-17
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Publication No.: US07422887B2Publication Date: 2008-09-09
- Inventor: Yuji Imai , Koji Wakimoto , Hiroaki Chiba
- Applicant: Yuji Imai , Koji Wakimoto , Hiroaki Chiba
- Applicant Address: JP Osaka
- Assignee: Mitsubishi Tanabe Pharma Corporation
- Current Assignee: Mitsubishi Tanabe Pharma Corporation
- Current Assignee Address: JP Osaka
- Agency: Browdy and Neimark, PLLC
- Priority: JP2002-008435 20020117
- International Application: PCT/JP03/00328 WO 20030117
- International Announcement: WO03/060132 WO 20030724
- Main IPC: C12N9/18
- IPC: C12N9/18 ; C12Q1/34 ; C12Q1/68 ; C07H21/04

Abstract:
To provide a novel phospholipase A2 (PLA2) associated with psoriasis, a nucleic acid encoding the same, a method for characterizing, identifying or screening an inhibitor for the PLA2 or a medicament; and a novel method for diagnosis or examination of psoriasis or the like. A polypeptide having the amino acid sequence shown in SEQ ID NO: 9, a conservative substitution variant thereof, a naturally occurring allelic variant thereof, or the like. A nucleic acid encoding the above-mentioned polypeptide, a complement thereof or the like. A method for characterizing, identifying or screening an inhibitor for the PLA2 or a medicament, using the above-mentioned polypeptide. An examination method for psoriasis, characterized by assaying an expression level of a gene consisting of the above-mentioned nucleic acid or the like.
Public/Granted literature
- US20050282161A1 Novel phospholipase a2 and gene thereof Public/Granted day:2005-12-22
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