发明授权
- 专利标题： Compounds and compositions as protein kinase inhibitors
- 专利标题（中）： 化合物和组合物作为蛋白激酶抑制剂
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申请号： US11570661申请日： 2005-06-23
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公开(公告)号： US07423038B2公开(公告)日： 2008-09-09
- 发明人: Pingda Ren , Xia Wang , Nathanael Schiander Gray , Yi Liu , Taebo Sim
- 申请人： Pingda Ren , Xia Wang , Nathanael Schiander Gray , Yi Liu , Taebo Sim
- 申请人地址： BM Hamilton
- 专利权人： IRM LLC (a Delaware Limited Liability Corporation)
- 当前专利权人： IRM LLC (a Delaware Limited Liability Corporation)
- 当前专利权人地址： BM Hamilton
- 代理机构： Genomics Institute of the Novartis Research Foundation
- 代理商 Scott W. Reid
- 国际申请： PCT/US2005/022463 WO 20050623
- 国际公布： WO2006/002367 WO 20060105
- 主分类号： A61K31/5355
- IPC分类号： A61K31/5355 ; C07D413/10 ; C07D475/00 ; A61P35/00
摘要：
The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders than involve abnormal activation of the Abl, Bcr-abl, Bmx, c-RAF, CSK, Fes, FGFR3, Flt3, GSK3β, IR, JNK1α 1, JNK2α 2, Lck, MKK4, MKK6, p70S6K, PDGFRα, Rsk1, SAPK2α, SAPK2β, Syk and Trkβ kinases.
公开/授权文献
- US20080113986A1 Compounds and Compositions as Protein Kinase Inhibitors 公开/授权日：2008-05-15