发明授权
US07425618B2 Stabilized anti-respiratory syncytial virus (RSV) antibody formulations
有权
稳定的抗呼吸道合胞病毒(RSV)抗体制剂
- 专利标题: Stabilized anti-respiratory syncytial virus (RSV) antibody formulations
- 专利标题(中): 稳定的抗呼吸道合胞病毒(RSV)抗体制剂
-
申请号: US10461863申请日: 2003-06-13
-
公开(公告)号: US07425618B2公开(公告)日: 2008-09-16
- 发明人: Cynthia N. Oliver , Christian B. Allan , Stephen T. Chang
- 申请人: Cynthia N. Oliver , Christian B. Allan , Stephen T. Chang
- 申请人地址: US MD Gaithersburg
- 专利权人: Medimmune, Inc.
- 当前专利权人: Medimmune, Inc.
- 当前专利权人地址: US MD Gaithersburg
- 代理机构: Jones Day
- 主分类号: C12P21/08
- IPC分类号: C12P21/08
摘要:
The present invention provides liquid formulations of antibodies or fragments thereof that immunospecifically bind to a respiratory syncytial virus (RSV) antigen, which formulations exhibit stability, low to undetectable levels of aggregation, and very little to no loss of the biological activities of the antibodies or antibody fragments, even during long periods of storage. In particular, the present invention provides liquid formulations of antibodies or fragments thereof that immunospecifically bind to a RSV antigen, which formulations are substantially free of surfactant, inorganic salts, and/or other common excipients. Furthermore, the invention provides methods of preventing, treating or ameliorating one or more symptoms associated with RSV infection utilizing the liquid formulations of the present invention.
公开/授权文献
信息查询