发明授权
- 专利标题： Aromatic sulfenates for type 1 phototherapy
- 专利标题（中）： 用于1型光疗法的芳香族亚磺酸盐
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申请号： US11276971申请日： 2006-03-20
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公开(公告)号： US07427657B1公开(公告)日： 2008-09-23
- 发明人: Raghavan Rajagopalan , Gary L. Cantrell , Samuel I. Achilefu , Joseph E. Bugaj , Richard B. Dorshow
- 申请人： Raghavan Rajagopalan , Gary L. Cantrell , Samuel I. Achilefu , Joseph E. Bugaj , Richard B. Dorshow
- 申请人地址： US MO St. Louis
- 专利权人： Mallinckrodt Inc.
- 当前专利权人： Mallinckrodt Inc.
- 当前专利权人地址： US MO St. Louis
- 代理机构： Thompson Hine LLP
- 主分类号： A61K38/16
- IPC分类号： A61K38/16
摘要：
The present invention discloses novel sulfenate derivatives and their bioconjugates for phototherapy of tumors and other lesions. The sulfenates of the present invention are designed to absorb low-energy ultraviolet, visible, or near-infrared (NIR) region of the electromagnetic spectrum. The phototherapeutic effect is caused by direct interaction of free radicals, the reactive intermediate produced upon photofragmentation of the sulfenate moiety, with the tissue of interest.
公开/授权文献
- US3800010A Phosphonopropionic acid amide derivatives 公开/授权日：1974-03-26
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