发明授权
- 专利标题： Preparation of compounds useful for the detection of hypoxia
- 专利标题（中）： 制备可用于检测缺氧的化合物
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申请号： US11363835申请日： 2006-02-28
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公开(公告)号： US07432295B2公开(公告)日： 2008-10-07
- 发明人: William R Dolbier , An-Rong Li , Cameron J Koch , Alexander V Kachur
- 申请人： William R Dolbier , An-Rong Li , Cameron J Koch , Alexander V Kachur
- 申请人地址： US PA Philadelphia
- 专利权人： The Trustees of The University of Pennsylvania
- 当前专利权人： The Trustees of The University of Pennsylvania
- 当前专利权人地址： US PA Philadelphia
- 代理机构： Woodcock Washburn, LLP
- 主分类号： A61K31/4172
- IPC分类号： A61K31/4172 ; C07D233/92
摘要：
Novel 18F-fluorine compounds useful for non-invasive imaging techniques such as PET, for detecting tissue hypoxia and methods for preparing them are disclosed. Novel intermediate compounds and methods for preparing them are also disclosed. Diagnostic kits useful in practicing the methods of claimed invention are also provided.
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