发明授权
- 专利标题： Pyridine derivatives
- 专利标题（中）： 吡啶衍生物
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申请号： US11240867申请日： 2005-09-30
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公开(公告)号： US07435743B2公开(公告)日： 2008-10-14
- 发明人: Toshiki Murata , Masaomi Umeda , Sachiko Sakakibara , Takashi Yoshiro , Hiroki Sato , Tsutomu Masuda , Yuji Koriyama , Mitsuiyuki Shimada , Takuya Shintani , Hiroshi Kadono , Timothy B. Lowinger , Karl B. Ziegelbauer , Kinji Fuchikami , Hiroshi Komura
- 申请人： Toshiki Murata , Masaomi Umeda , Sachiko Sakakibara , Takashi Yoshiro , Hiroki Sato , Tsutomu Masuda , Yuji Koriyama , Mitsuiyuki Shimada , Takuya Shintani , Hiroshi Kadono , Timothy B. Lowinger , Karl B. Ziegelbauer , Kinji Fuchikami , Hiroshi Komura
- 申请人地址： DE Leverkusen
- 专利权人： Bayer Aktiengesellschaft
- 当前专利权人： Bayer Aktiengesellschaft
- 当前专利权人地址： DE Leverkusen
- 代理机构： Edwards Angell Palmer & Dodge LLP
- 代理商 Barry Kramer; Ralph A. Loren
- 优先权： JP2000-289173 20000922
- 主分类号： A61K31/4418
- IPC分类号： A61K31/4418 ; A61K31/444 ; A61K31/4436 ; C07D213/22 ; C07D409/04 ; C07D213/73
摘要：
Pyrimidine compounds of general formula: wherein —R1 represents in which R11 is hydrogen, C1-6 alkyl, halogen, hydroxy, C1-12 alkoxy, nitro, amino, C1-6 alkylsulfonylamino, C1-6 alkoxycarbonyl, C1-6 alkylamino, di (C1-6 alkyl)amino, C1-6 alkanoylamino, phenyl C1-6 alkylamino, phenylsulfonylamino, or —O—(CH2)n—R111; R2 represents hydrogen or halogen; R3 represents hydrogen, —CR31R32R33; R4 is hydrogen, carbamoyl, CN, carboxyl, etc.; R5 is amino, C1-6 alkylamino, di C1-6 alkylamino, etc. or salt thereof. The compound has an excellent anti-inflammatory activity, and other biological activity.
公开/授权文献
- US20060205676A1 Pyridine derivatives 公开/授权日：2006-09-14
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