发明授权
- 专利标题: Yeast-based therapeutic for chronic hepatitis C infection
- 专利标题(中): 基于酵母的慢性丙型肝炎感染治疗
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申请号: US11254252申请日: 2005-10-18
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公开(公告)号: US07439042B2公开(公告)日: 2008-10-21
- 发明人: Richard C. Duke , Alex Franzusoff , Aurelia Haller , Thomas H. King
- 申请人: Richard C. Duke , Alex Franzusoff , Aurelia Haller , Thomas H. King
- 申请人地址: US CO Louisville
- 专利权人: GlobeImmune, Inc.
- 当前专利权人: GlobeImmune, Inc.
- 当前专利权人地址: US CO Louisville
- 代理机构: Sheridan Ross P.C.
- 代理商 Angela Dallas Sebor
- 主分类号: C12N15/33
- IPC分类号: C12N15/33
摘要:
Disclosed are compositions, including vaccines, and methods for vaccinating an animal against hepatitis C virus (HCV) and for treating or preventing hepatitis C viral infection in an animal. The invention includes a variety of novel HCV fusion proteins that can be used directly as a vaccine or in conjunction with a yeast-based vaccine vehicle to elicit an immune response against HCV in an animal. The invention also includes the use of the HCV fusion gene and protein described herein in any diagnostic or therapeutic protocol for the detection and/or treatment or prevention of HCV infection.