发明授权
US07439351B2 2′ or 3′ -deoxy and 2′, 3′-dideoxy-β-L-pentofuranonucleo-side compounds, method of preparation and application in therapy, especially as anti-viral agents
有权
2'或3'-脱氧和2',3'-二脱氧-β-L-戊呋喃核苷酸化合物,其制备方法和在治疗中的应用,特别是作为抗病毒剂
- 专利标题: 2′ or 3′ -deoxy and 2′, 3′-dideoxy-β-L-pentofuranonucleo-side compounds, method of preparation and application in therapy, especially as anti-viral agents
- 专利标题(中): 2'或3'-脱氧和2',3'-二脱氧-β-L-戊呋喃核苷酸化合物,其制备方法和在治疗中的应用,特别是作为抗病毒剂
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申请号: US10672585申请日: 2003-09-26
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公开(公告)号: US07439351B2公开(公告)日: 2008-10-21
- 发明人: Gilles Gosselin , Jean-Louis Imbach , Anne-Marie Aubertin , Jean-Pierre Sommmadossi , Raymond F. Schinazi
- 申请人: Gilles Gosselin , Jean-Louis Imbach , Anne-Marie Aubertin , Jean-Pierre Sommmadossi , Raymond F. Schinazi
- 申请人地址: US AL Birmingham US GA Atlanta FR Paris
- 专利权人: The UAB Research Foundation,Emory University,Centre National de la Recherche Scientifique (CNSR)
- 当前专利权人: The UAB Research Foundation,Emory University,Centre National de la Recherche Scientifique (CNSR)
- 当前专利权人地址: US AL Birmingham US GA Atlanta FR Paris
- 代理机构: King & Spalding
- 优先权: FR9310798 19930910; WOPCT/FR94/01066 19990909
- 主分类号: C07H19/073
- IPC分类号: C07H19/073 ; C07H19/173
摘要:
Method for the sterospecific preparation of 2′ or 3′ deoxy and 2′,3′-dideoxy-β-L-pentafuranonucleoside compounds. 2′ or 3′ deoxy and 2′,3′-dideoxy-β-L-pentofuranonucleoside compounds are also described. Finally, the invention concerns the use of these compounds, and particularly 2′,3′dideoxy-β-L-fluorocytidine, as drugs, and especially as anti-viral agents.
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